Asquith, Christopher R M <br/><br/>
Targeting the Water Network in Cyclin G-Associated Kinase (GAK) with 4-Anilino-quin(az)oline Inhibitors.  [electronic resource] 

 -  ChemMedChem  07 2020 
 - 1200-1215 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1860-7187 
<br/><br/><label>Standard No.: </label>10.1002/cmdc.202000150  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Crystallography, X-Ray<br/>Dose-Response Relationship, Drug<br/>HEK293 Cells<br/>Humans<br/>Intracellular Signaling Peptides and Proteins--antagonists & inhibitors<br/>Models, Molecular<br/>Molecular Structure<br/>Protein Kinase Inhibitors--chemical synthesis<br/>Protein Serine-Threonine Kinases--antagonists & inhibitors<br/>Quinazolines--chemical synthesis<br/>Structure-Activity Relationship<br/>Water--chemistry