Vinckier, Nicholas K

LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development. [electronic resource] - Nature communications 04 2020 - 2082 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

2041-1723

10.1038/s41467-020-16017-x doi


Adult
Animals
Base Sequence
Cell Differentiation--drug effects
Endocrine Cells--cytology
Enhancer Elements, Genetic--genetics
Female
Gene Expression Regulation, Developmental--drug effects
Gene Silencing--drug effects
Histone Demethylases--metabolism
Human Embryonic Stem Cells--cytology
Humans
Islets of Langerhans--cytology
Male
Mice
Signal Transduction--drug effects
Transcription Factors--metabolism
Tretinoin--metabolism
Young Adult