Vinckier, Nicholas K
LSD1-mediated enhancer silencing attenuates retinoic acid signalling during pancreatic endocrine cell development. [electronic resource]
- Nature communications 04 2020
- 2082 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
2041-1723
10.1038/s41467-020-16017-x doi
Adult
Animals
Base Sequence
Cell Differentiation--drug effects
Endocrine Cells--cytology
Enhancer Elements, Genetic--genetics
Female
Gene Expression Regulation, Developmental--drug effects
Gene Silencing--drug effects
Histone Demethylases--metabolism
Human Embryonic Stem Cells--cytology
Humans
Islets of Langerhans--cytology
Male
Mice
Signal Transduction--drug effects
Transcription Factors--metabolism
Tretinoin--metabolism
Young Adult