TY - GEN AU - Hu,Weiwei AU - Zheng,Shufang AU - Guo,Haixin AU - Dai,Beiying AU - Ni,Jiaping AU - Shi,Yaohong AU - Bian,Hanrui AU - Li,Lanxin AU - Shen,Yumeng AU - Wu,Mo AU - Tian,Zhoutong AU - Liu,Guilai AU - Hossain,Md Amir AU - Yang,Hongbao AU - Wang,Duowei AU - Zhang,Qin AU - Yu,Jun AU - Birnbaumer,Lutz AU - Feng,Jifeng AU - Yu,Decai AU - Yang,Yong TI - PLAGL2-EGFR-HIF-1/2α Signaling Loop Promotes HCC Progression and Erlotinib Insensitivity SN - 1527-3350 PY - 2021///0809 KW - Adult KW - Aged KW - Animals KW - Basic Helix-Loop-Helix Transcription Factors KW - metabolism KW - Carcinoma, Hepatocellular KW - drug therapy KW - Cell Line, Tumor KW - Cell Movement KW - genetics KW - Cell Proliferation KW - DNA-Binding Proteins KW - Disease Progression KW - Drug Resistance, Neoplasm KW - ErbB Receptors KW - antagonists & inhibitors KW - Erlotinib Hydrochloride KW - pharmacology KW - Feedback, Physiological KW - Female KW - Gene Expression Regulation, Neoplastic KW - Gene Knockdown Techniques KW - Humans KW - Hypoxia-Inducible Factor 1, alpha Subunit KW - Kaplan-Meier Estimate KW - Liver KW - pathology KW - Liver Neoplasms KW - Male KW - Mice KW - Middle Aged KW - Neoplasm Invasiveness KW - RNA-Binding Proteins KW - RNA-Seq KW - Signal Transduction KW - Transcription Factors KW - Tumor Hypoxia KW - Up-Regulation KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/hep.31293 ER -