Liao, Qinghong

Design, synthesis and biological evaluation of novel carboline-cinnamic acid hybrids as multifunctional agents for treatment of Alzheimer's disease. [electronic resource] - Bioorganic chemistry 06 2020 - 103844 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1090-2120

10.1016/j.bioorg.2020.103844 doi


Alzheimer Disease--drug therapy
Amyloid beta-Peptides--antagonists & inhibitors
Animals
Carbolines--chemistry
Cell Survival--drug effects
Cinnamates--chemistry
Dose-Response Relationship, Drug
Drug Design
Humans
Male
Maze Learning--drug effects
Mice
Mice, Inbred ICR
Molecular Structure
Neuroprotective Agents--chemical synthesis
Peptide Fragments--antagonists & inhibitors
Protein Aggregates--drug effects
Rats
Structure-Activity Relationship
Tumor Cells, Cultured