Hendriks, Delilah F G <br/><br/>
Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three-Dimensional Spheroid Cultures of Primary Human Hepatocytes.  [electronic resource] 

 -  Clinical pharmacology and therapeutics  10 2020 
 - 844-855 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1532-6535 
<br/><br/><label>Standard No.: </label>10.1002/cpt.1860  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Cell Culture Techniques<br/>Cells, Cultured<br/>Constitutive Androstane Receptor<br/>Cytochrome P-450 CYP3A--metabolism<br/>Cytochrome P-450 CYP3A Inducers--pharmacology<br/>Drug Evaluation, Preclinical<br/>Drug Interactions<br/>ErbB Receptors--drug effects<br/>Extracellular Signal-Regulated MAP Kinases--metabolism<br/>Hepatocytes--drug effects<br/>Humans<br/>Phosphorylation<br/>Pregnane X Receptor--drug effects<br/>Receptors, Cytoplasmic and Nuclear--drug effects<br/>Signal Transduction<br/>Spheroids, Cellular