TY - GEN AU - Lee,Jenny H AU - Shklovskaya,Elena AU - Lim,Su Yin AU - Carlino,Matteo S AU - Menzies,Alexander M AU - Stewart,Ashleigh AU - Pedersen,Bernadette AU - Irvine,Malama AU - Alavi,Sara AU - Yang,Jean Y H AU - Strbenac,Dario AU - Saw,Robyn P M AU - Thompson,John F AU - Wilmott,James S AU - Scolyer,Richard A AU - Long,Georgina V AU - Kefford,Richard F AU - Rizos,Helen TI - Transcriptional downregulation of MHC class I and melanoma de- differentiation in resistance to PD-1 inhibition SN - 2041-1723 PY - 2020///0804 KW - Adult KW - Aged KW - Aged, 80 and over KW - Cell Differentiation KW - Cell Line, Tumor KW - Down-Regulation KW - Drug Resistance, Neoplasm KW - genetics KW - Female KW - Gene Expression Regulation, Neoplastic KW - Histocompatibility Antigens Class I KW - Humans KW - Immunotherapy KW - Male KW - Melanoma KW - Middle Aged KW - Programmed Cell Death 1 Receptor KW - drug effects KW - Transcriptome KW - Tumor Microenvironment N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41467-020-15726-7 ER -