TY - GEN AU - Behnisch-Cornwell,Steven AU - Bandaru,Siva Sankar Murthy AU - Napierkowski,Martin AU - Wolff,Lisa AU - Zubair,Muhammad AU - Urbainsky,Claudia AU - Lillig,Christopher AU - Schulzke,Carola AU - Bednarski,Patrick J TI - Pentathiepins: A Novel Class of Glutathione Peroxidase 1 Inhibitors that Induce Oxidative Stress, Loss of Mitochondrial Membrane Potential and Apoptosis in Human Cancer Cells SN - 1860-7187 PY - 2021///0614 KW - Antineoplastic Agents KW - chemical synthesis KW - Apoptosis KW - drug effects KW - Cell Proliferation KW - Cell Survival KW - Dose-Response Relationship, Drug KW - Drug Screening Assays, Antitumor KW - Enzyme Inhibitors KW - Glutathione Peroxidase KW - antagonists & inhibitors KW - Heterocyclic Compounds KW - Humans KW - Membrane Potential, Mitochondrial KW - Molecular Structure KW - Oxidative Stress KW - Structure-Activity Relationship KW - Sulfides KW - Tumor Cells, Cultured KW - Glutathione Peroxidase GPX1 N1 - Publication Type: Journal Article UR - https://doi.org/10.1002/cmdc.202000160 ER -