Behnisch-Cornwell, Steven Pentathiepins: A Novel Class of Glutathione Peroxidase 1 Inhibitors that Induce Oxidative Stress, Loss of Mitochondrial Membrane Potential and Apoptosis in Human Cancer Cells. [electronic resource] - ChemMedChem 08 2020 - 1515-1528 p. digital Publication Type: Journal Article ISSN: 1860-7187 Standard No.: 10.1002/cmdc.202000160 doi Subjects--Topical Terms: Antineoplastic Agents--chemical synthesisApoptosis--drug effectsCell Proliferation--drug effectsCell Survival--drug effectsDose-Response Relationship, DrugDrug Screening Assays, AntitumorEnzyme Inhibitors--chemical synthesisGlutathione Peroxidase--antagonists & inhibitorsHeterocyclic Compounds--chemical synthesisHumansMembrane Potential, Mitochondrial--drug effectsMolecular StructureOxidative Stress--drug effectsStructure-Activity RelationshipSulfides--chemical synthesisTumor Cells, CulturedGlutathione Peroxidase GPX1