The genomic landscape of undifferentiated embryonal sarcoma of the liver is typified by C19MC structural rearrangement and overexpression combined with TP53 mutation or loss. [electronic resource]
- PLoS genetics 04 2020
- e1008642 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1553-7404
10.1371/journal.pgen.1008642 doi
Aneuploidy Child Child, Preschool Chromosome Breakpoints Chromosomes, Human, Pair 19--genetics Female Gene Expression Regulation, Neoplastic Genes, ras--genetics Genomic Instability--genetics Humans Infant Liver Neoplasms--genetics Male MicroRNAs--genetics Mutation Neoplasms, Germ Cell and Embryonal--genetics Sarcoma--genetics Transcription Initiation Site Tumor Suppressor Protein p53--deficiency Up-Regulation