TY - GEN AU - Yang,Hui-Hui AU - Duan,Jia-Xi AU - Liu,Shao-Kun AU - Xiong,Jian-Bing AU - Guan,Xin-Xin AU - Zhong,Wen-Jing AU - Sun,Chen-Chen AU - Zhang,Chen-Yu AU - Luo,Xiao-Qin AU - Zhang,Yan-Feng AU - Chen,Ping AU - Hammock,Bruce D AU - Hwang,Sung Hee AU - Jiang,Jian-Xin AU - Zhou,Yong AU - Guan,Cha-Xiang TI - A COX-2/sEH dual inhibitor PTUPB alleviates lipopolysaccharide-induced acute lung injury in mice by inhibiting NLRP3 inflammasome activation SN - 1838-7640 PY - 2021///0513 KW - Acute Lung Injury KW - chemically induced KW - Animals KW - Cells, Cultured KW - Cyclooxygenase 2 KW - chemistry KW - Cyclooxygenase 2 Inhibitors KW - pharmacology KW - Disease Models, Animal KW - Enzyme Inhibitors KW - Epoxide Hydrolases KW - antagonists & inhibitors KW - Inflammasomes KW - drug effects KW - Lipopolysaccharides KW - Lung KW - Macrophages KW - metabolism KW - Male KW - Mice KW - Mice, Inbred C57BL KW - NLR Family, Pyrin Domain-Containing 3 Protein KW - Oxidative Stress N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.7150/thno.43108 ER -