Sbardella, Diego <br/><br/>
Structural and functional evidence for citicoline binding and modulation of 20S proteasome activity: Novel insights into its pro-proteostatic effect.  [electronic resource] 

 -  Biochemical pharmacology  07 2020 
 - 113977 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1873-2968 
<br/><br/><label>Standard No.: </label>10.1016/j.bcp.2020.113977  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Allosteric Regulation<br/>Amino Acid Sequence<br/>Binding Sites<br/>Cell Line, Tumor<br/>Cytidine Diphosphate Choline--chemistry<br/>Gene Expression<br/>Humans<br/>Kinetics<br/>Molecular Docking Simulation<br/>Neurons--drug effects<br/>Neuroprotective Agents--chemistry<br/>Nootropic Agents--chemistry<br/>Proteasome Endopeptidase Complex--chemistry<br/>Proteasome Inhibitors--chemistry<br/>Protein Binding<br/>Protein Conformation, alpha-Helical<br/>Protein Conformation, beta-Strand<br/>Protein Interaction Domains and Motifs<br/>Proteostasis--drug effects<br/>Recombinant Proteins--chemistry<br/>Sequence Alignment<br/>Sequence Homology, Amino Acid<br/>Substrate Specificity<br/>Thermodynamics<br/>alpha-Synuclein--chemistry