Šála, Michal <br/><br/>
Novel Human Neutral Sphingomyelinase 2 Inhibitors as Potential Therapeutics for Alzheimer's Disease.  [electronic resource] 

 -  Journal of medicinal chemistry  06 2020 
 - 6028-6056 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/acs.jmedchem.0c00278  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alzheimer Disease--drug therapy<br/>Animals<br/>Body Weight--drug effects<br/>Brain--metabolism<br/>Disease Models, Animal<br/>Enzyme Inhibitors--chemistry<br/>Exosomes--metabolism<br/>Female<br/>Humans<br/>Male<br/>Mice<br/>Mice, Transgenic<br/>Pyridazines--chemistry<br/>Sphingomyelin Phosphodiesterase--antagonists & inhibitors<br/>Structure-Activity Relationship