TY - GEN AU - Sun,Lin AU - Dick,Alexej AU - Meuser,Megan E AU - Huang,Tianguang AU - Zalloum,Waleed A AU - Chen,Chin-Ho AU - Cherukupalli,Srinivasulu AU - Xu,Shujing AU - Ding,Xiao AU - Gao,Ping AU - Kang,Dongwei AU - De Clercq,Erik AU - Pannecouque,Christophe AU - Cocklin,Simon AU - Lee,Kuo-Hsiung AU - Liu,Xinyong AU - Zhan,Peng TI - Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities SN - 1520-4804 PY - 2020///1102 KW - Animals KW - Anti-HIV Agents KW - chemical synthesis KW - Capsid Proteins KW - antagonists & inhibitors KW - Cell Line, Tumor KW - Drug Design KW - Female KW - HIV-1 KW - chemistry KW - HIV-2 KW - Humans KW - Male KW - Mice KW - Microsomes, Liver KW - metabolism KW - Molecular Structure KW - Phenylalanine KW - analogs & derivatives KW - Rats, Sprague-Dawley KW - Structure-Activity Relationship KW - Sulfonamides KW - Virus Replication KW - drug effects N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/acs.jmedchem.0c00015 ER -