Fenerich, Bruna Alves

NT157 has antineoplastic effects and inhibits IRS1/2 and STAT3/5 in JAK2 [electronic resource] - Signal transduction and targeted therapy 01 2020 - 5 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2059-3635

10.1038/s41392-019-0102-5 doi


Apoptosis--drug effects
Cell Cycle Checkpoints--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
Cell Survival--drug effects
Gene Expression Regulation, Neoplastic--drug effects
Humans
Insulin Receptor Substrate Proteins--antagonists & inhibitors
Janus Kinase 2--genetics
Myeloproliferative Disorders--drug therapy
Polycythemia Vera--drug therapy
Pyrogallol--analogs & derivatives
STAT3 Transcription Factor--antagonists & inhibitors
STAT5 Transcription Factor--antagonists & inhibitors
Sulfonamides--pharmacology