TY  - GEN
AU  - Satheeshkumar,Rajendran
AU  - Zhu,Rui
AU  - Feng,Bo
AU  - Huang,Chao
AU  - Gao,Ya
AU  - Gao,Li-Xin
AU  - Shen,Chao
AU  - Hou,Ting-Jun
AU  - Xu,Lei
AU  - Li,Jia
AU  - Zhu,Yun-Long
AU  - Zhou,Yu-Bo
AU  - Wang,Wen-Long
TI  - Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors
SN  - 1464-3405
PY  - 2021///0430
KW  - Amides
KW  - chemistry
KW  - Binding Sites
KW  - Enzyme Inhibitors
KW  - chemical synthesis
KW  - Heterocyclic Compounds
KW  - Humans
KW  - Kinetics
KW  - Molecular Docking Simulation
KW  - Protein Tyrosine Phosphatase, Non-Receptor Type 1
KW  - antagonists & inhibitors
KW  - Protein Tyrosine Phosphatase, Non-Receptor Type 11
KW  - Structure-Activity Relationship
KW  - src Homology Domains
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.bmcl.2020.127170
ER  -