TY - GEN AU - Lee,Jii Bum AU - Kim,Han Sang AU - Jung,Inkyung AU - Shin,Sang Joon AU - Beom,Seung Hoon AU - Chang,Jee Suk AU - Koom,Woong Sub AU - Kim,Tae Il AU - Hur,Hyuk AU - Min,Byung Soh AU - Kim,Nam Kyu AU - Park,Sohee AU - Jeong,Seung-Yong AU - Baek,Jeong-Heum AU - Kim,Seon Hahn AU - Lim,Joon Seok AU - Lee,Kang Young AU - Ahn,Joong Bae TI - Upfront radical surgery with total mesorectal excision followed by adjuvant FOLFOX chemotherapy for locally advanced rectal cancer (TME-FOLFOX): an open-label, multicenter, phase II randomized controlled trial SN - 1745-6215 PY - 2021///0118 KW - Antineoplastic Combined Chemotherapy Protocols KW - therapeutic use KW - Chemoradiotherapy KW - methods KW - Chemotherapy, Adjuvant KW - Clinical Trials, Phase II as Topic KW - Disease-Free Survival KW - Dose-Response Relationship, Drug KW - Drug Administration Schedule KW - Fluorouracil KW - Humans KW - Leucovorin KW - Multicenter Studies as Topic KW - Neoadjuvant Therapy KW - Neoplasm Invasiveness KW - Neoplasm Staging KW - Organoplatinum Compounds KW - Preoperative Care KW - Prognosis KW - Prospective Studies KW - Randomized Controlled Trials as Topic KW - Rectal Neoplasms KW - drug therapy KW - Republic of Korea KW - Survival Analysis KW - Treatment Outcome N1 - Publication Type: Clinical Trial Protocol; Comparative Study; Journal Article UR - https://doi.org/10.1186/s13063-020-04266-6 ER -