Upfront radical surgery with total mesorectal excision followed by adjuvant FOLFOX chemotherapy for locally advanced rectal cancer (TME-FOLFOX): an open-label, multicenter, phase II randomized controlled trial. [electronic resource]
- Trials Apr 2020
- 320 p. digital
Antineoplastic Combined Chemotherapy Protocols--therapeutic use Chemoradiotherapy--methods Chemotherapy, Adjuvant Clinical Trials, Phase II as Topic Disease-Free Survival Dose-Response Relationship, Drug Drug Administration Schedule Fluorouracil--therapeutic use Humans Leucovorin--therapeutic use Multicenter Studies as Topic Neoadjuvant Therapy--methods Neoplasm Invasiveness Neoplasm Staging Organoplatinum Compounds--therapeutic use Preoperative Care--methods Prognosis Prospective Studies Randomized Controlled Trials as Topic Rectal Neoplasms--drug therapy Republic of Korea Survival Analysis Treatment Outcome