Sheahan, Timothy P <br/><br/>
An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice.  [electronic resource] 

 -  Science translational medicine  04 2020 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1946-6242 
<br/><br/><label>Standard No.: </label>10.1126/scitranslmed.abb5883  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenosine Monophosphate--administration & dosage<br/>Alanine--administration & dosage<br/>Animals<br/>Antibiotic Prophylaxis<br/>Antiviral Agents--administration & dosage<br/>Betacoronavirus--physiology<br/>COVID-19<br/>Cell Line<br/>Coronavirus Infections--drug therapy<br/>Cytidine--administration & dosage<br/>Disease Models, Animal<br/>Drug Resistance, Viral<br/>Humans<br/>Hydroxylamines<br/>Lung--pathology<br/>Mice<br/>Mice, Inbred C57BL<br/>Middle East Respiratory Syndrome Coronavirus--physiology<br/>Models, Molecular<br/>Mutation--drug effects<br/>Pandemics<br/>Pneumonia, Viral--drug therapy<br/>Primary Cell Culture<br/>RNA, Viral<br/>RNA-Dependent RNA Polymerase--chemistry<br/>Random Allocation<br/>Respiratory System--cytology<br/>Ribonucleosides--administration & dosage<br/>SARS-CoV-2<br/>Virus Replication--drug effects