Composition and Orientation of the Core Region of Novel HIV-1 Entry Inhibitors Influences Metabolic Stability. [electronic resource]
- Molecules (Basel, Switzerland) Mar 2020
Publication Type: Journal Article
1420-3049
10.3390/molecules25061430 doi
Anti-HIV Agents--pharmacology Azabicyclo Compounds--chemical synthesis Azetidines--chemical synthesis Chromatography, Liquid HEK293 Cells HIV Core Protein p24--chemistry HIV Fusion Inhibitors--metabolism HIV Infections--drug therapy HIV-1--drug effects Humans Microsomes, Liver--virology Organophosphates--chemistry Piperazines--chemistry Protein Binding Pyrrolidines--chemical synthesis Tandem Mass Spectrometry Triazoles--chemical synthesis