TY - GEN AU - Park,Heejun AU - Jin Seo,Hye AU - Hong,Seung-Hyeon AU - Ha,Eun-Sol AU - Lee,Sibeum AU - Kim,Jeong-Soo AU - Baek,In-Hwan AU - Kim,Min-Soo AU - Hwang,Sung-Joo TI - Characterization and therapeutic efficacy evaluation of glimepiride and L-arginine co-amorphous formulation prepared by supercritical antisolvent process: Influence of molar ratio and preparation methods SN - 1873-3476 PY - 2021///0201 KW - Administration, Oral KW - Animals KW - Arginine KW - administration & dosage KW - Blood Glucose KW - analysis KW - Calorimetry, Differential Scanning KW - Chemistry, Pharmaceutical KW - Diabetes Mellitus, Experimental KW - blood KW - Diabetes Mellitus, Type 2 KW - Drug Combinations KW - Drug Compounding KW - methods KW - Drug Liberation KW - Humans KW - Hypoglycemic Agents KW - Magnetic Resonance Spectroscopy KW - Male KW - Particle Size KW - Powder Diffraction KW - Rats KW - Solubility KW - Solvents KW - chemistry KW - Spectroscopy, Fourier Transform Infrared KW - Streptozocin KW - toxicity KW - Sulfonylurea Compounds KW - X-Ray Diffraction N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.ijpharm.2020.119232 ER -