TY - GEN AU - Burgess,Teresa L AU - Amason,Joshua D AU - Rubin,Jeffrey S AU - Duveau,Damien Y AU - Lamy,Laurence AU - Roberts,David D AU - Farrell,Catherine L AU - Inglese,James AU - Thomas,Craig J AU - Miller,Thomas W TI - A homogeneous SIRPα-CD47 cell-based, ligand-binding assay: Utility for small molecule drug development in immuno-oncology SN - 1932-6203 PY - 2020///0706 KW - Adaptive Immunity KW - drug effects KW - Aminoacyltransferases KW - antagonists & inhibitors KW - Antigens, Differentiation KW - chemistry KW - CD47 Antigen KW - Drug Development KW - Gene Expression Regulation, Neoplastic KW - High-Throughput Screening Assays KW - methods KW - Humans KW - Immunotherapy KW - Jurkat Cells KW - Laser Scanning Cytometry KW - Ligands KW - Medical Oncology KW - trends KW - Neoplasms KW - drug therapy KW - Phagocytosis KW - Protein Interaction Maps KW - genetics KW - Receptors, Immunologic KW - Small Molecule Libraries N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1371/journal.pone.0226661 ER -