TY - GEN AU - Bielack,S S AU - Cox,M C AU - Nathrath,M AU - Apel,K AU - Blattmann,C AU - Holl,T AU - Jenewein,R AU - Klenk,U AU - Klothaki,P AU - Müller-Abt,P AU - Ortega-Lawerenz,S AU - Reynolds,M AU - Scheer,M AU - Simon-Klingenstein,K AU - Stegmaier,S AU - Tupper,R AU - Vokuhl,C AU - von Kalle,T TI - Rapid, complete and sustained tumour response to the TRK inhibitor larotrectinib in an infant with recurrent, chemotherapy-refractory infantile fibrosarcoma carrying the characteristic ETV6-NTRK3 gene fusion SN - 1569-8041 PY - 2020///0911 KW - Drug Resistance, Neoplasm KW - Fibrosarcoma KW - drug therapy KW - Humans KW - Infant KW - Infant, Newborn KW - Male KW - Neoplasm Recurrence, Local KW - Oncogene Proteins, Fusion KW - genetics KW - Protein Kinase Inhibitors KW - therapeutic use KW - Pyrazoles KW - Pyrimidines KW - Salvage Therapy N1 - Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1093/annonc/mdz382 ER -