Rapid, complete and sustained tumour response to the TRK inhibitor larotrectinib in an infant with recurrent, chemotherapy-refractory infantile fibrosarcoma carrying the characteristic ETV6-NTRK3 gene fusion. [electronic resource]
- Annals of oncology : official journal of the European Society for Medical Oncology 11 2019
- viii31-viii35 p. digital
Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't
1569-8041
10.1093/annonc/mdz382 doi
Drug Resistance, Neoplasm Fibrosarcoma--drug therapy Humans Infant Infant, Newborn Male Neoplasm Recurrence, Local--drug therapy Oncogene Proteins, Fusion--genetics Protein Kinase Inhibitors--therapeutic use Pyrazoles--therapeutic use Pyrimidines--therapeutic use Salvage Therapy