TY  - GEN
AU  - Tochigi,Taro
AU  - Miyamoto,Toshihiro
AU  - Hatakeyama,Kiwamu
AU  - Sakoda,Teppei
AU  - Ishihara,Daisuke
AU  - Irifune,Hidetoshi
AU  - Shima,Takahiro
AU  - Kato,Koji
AU  - Maeda,Takahiro
AU  - Ito,Takumi
AU  - Handa,Hiroshi
AU  - Akashi,Koichi
AU  - Kikushige,Yoshikane
TI  - Aromatase is a novel neosubstrate of cereblon responsible for immunomodulatory drug-induced thrombocytopenia
SN  - 1528-0020
PY  - 2021///0208
KW  - Adaptor Proteins, Signal Transducing
KW  - metabolism
KW  - Aged
KW  - Aged, 80 and over
KW  - Aromatase
KW  - Female
KW  - HEK293 Cells
KW  - Humans
KW  - Immunologic Factors
KW  - adverse effects
KW  - K562 Cells
KW  - Male
KW  - Megakaryocytes
KW  - drug effects
KW  - Middle Aged
KW  - Multiple Myeloma
KW  - drug therapy
KW  - Myelodysplastic Syndromes
KW  - Myelopoiesis
KW  - Substrate Specificity
KW  - Thrombocytopenia
KW  - chemically induced
KW  - Ubiquitin-Protein Ligases
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1182/blood.2019003749
ER  -