Mesquita, Inês <br/><br/>
The Absence of HIF-1α Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis.  [electronic resource] 

 -  Cell reports  03 2020 
 - 4052-4064.e7 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>2211-1247 
<br/><br/><label>Standard No.: </label>10.1016/j.celrep.2020.02.098  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Disease Resistance<br/>Disease Susceptibility<br/>Genetic Variation<br/>Humans<br/>Hypoxia-Inducible Factor 1, alpha Subunit--genetics<br/>Leishmania donovani--physiology<br/>Leishmaniasis, Visceral--metabolism<br/>Lipids--biosynthesis<br/>Lipogenesis<br/>Macrophages--parasitology<br/>Membrane Proteins--metabolism<br/>Mice, Inbred BALB C<br/>Mice, Inbred C57BL<br/>Mitochondrial Proteins--metabolism<br/>Myeloid Cells--metabolism<br/>Signal Transduction<br/>Sterol Regulatory Element Binding Protein 1--metabolism<br/>TOR Serine-Threonine Kinases--metabolism<br/>Up-Regulation