Type 5 17-hydroxysteroid dehydrogenase/prostaglandin F synthase (AKR1C3) inhibition and potential anti-proliferative activity of cholest-4-ene-3,6-dione in MCF-7 breast cancer cells. [electronic resource]
- Steroids 07 2020
- 108638 p. digital
Publication Type: Journal Article
1878-5867
10.1016/j.steroids.2020.108638 doi
Aldo-Keto Reductase Family 1 Member C3--antagonists & inhibitors Antineoplastic Agents--chemical synthesis Apoptosis--drug effects Cell Cycle--drug effects Cell Proliferation--drug effects Dose-Response Relationship, Drug Drug Screening Assays, Antitumor Enzyme Inhibitors--chemical synthesis Humans MCF-7 Cells Molecular Structure Pregnenediones--chemical synthesis Structure-Activity Relationship