TY  - GEN
AU  - Gangopadhyay,Kaustav
AU  - Manna,Bharat
AU  - Roy,Swarnendu
AU  - Kumari,Sunitha
AU  - Debnath,Olivia
AU  - Chowdhury,Subhankar
AU  - Ghosh,Amit
AU  - Das,Rahul
TI  - An allosteric hot spot in the tandem-SH2 domain of ZAP-70 regulates T-cell signaling
SN  - 1470-8728
PY  - 2020///1027
KW  - Allosteric Regulation
KW  - Allosteric Site
KW  - Animals
KW  - Arthritis, Rheumatoid
KW  - genetics
KW  - Disease Models, Animal
KW  - Escherichia coli
KW  - Immunoreceptor Tyrosine-Based Activation Motif
KW  - Mice
KW  - Molecular Dynamics Simulation
KW  - Phosphorylation
KW  - Point Mutation
KW  - Receptors, Antigen, T-Cell
KW  - metabolism
KW  - Signal Transduction
KW  - Syk Kinase
KW  - T-Lymphocytes
KW  - ZAP-70 Protein-Tyrosine Kinase
KW  - chemistry
KW  - src Homology Domains
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1042/BCJ20190879
ER  -