Lin, Kevin H <br/><br/>
Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer.  [electronic resource] 

 -  Nature genetics  04 2020 
 - 408-417 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1546-1718 
<br/><br/><label>Standard No.: </label>10.1038/s41588-020-0590-9  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adaptation, Physiological--genetics<br/>Animals<br/>Biological Evolution<br/>CRISPR-Cas Systems--genetics<br/>Cell Line<br/>Cell Line, Tumor<br/>Drug Resistance, Neoplasm--genetics<br/>Environment<br/>Genetic Fitness--genetics<br/>Genetic Pleiotropy--genetics<br/>HEK293 Cells<br/>HL-60 Cells<br/>Humans<br/>Mice<br/>Neoplasms--genetics<br/>Nuclear Proteins--genetics<br/>Phenotype<br/>Quantitative Trait Loci--genetics<br/>Transcription Factors--genetics