Álvarez, Raquel <br/><br/>
Potent colchicine-site ligands with improved intrinsic solubility by replacement of the 3,4,5-trimethoxyphenyl ring with a 2-methylsulfanyl-6-methoxypyridine ring.  [electronic resource] 

 -  Bioorganic chemistry  05 2020 
 - 103755 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1090-2120 
<br/><br/><label>Standard No.: </label>10.1016/j.bioorg.2020.103755  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--chemical synthesis<br/>Cell Cycle--drug effects<br/>Cell Proliferation--drug effects<br/>Colchicine--chemical synthesis<br/>Dose-Response Relationship, Drug<br/>Drug Screening Assays, Antitumor<br/>Humans<br/>Ligands<br/>Molecular Structure<br/>Polymerization--drug effects<br/>Pyridines--chemistry<br/>Solubility<br/>Structure-Activity Relationship<br/>Tubulin--metabolism<br/>Tumor Cells, Cultured