TY - GEN AU - Tang,Yan-Ling AU - Zheng,Xi AU - Qi,Yan AU - Pu,Xiao-Jia AU - Liu,Bei AU - Zhang,Xia AU - Li,Xiao-Si AU - Xiao,Wei-Lie AU - Wan,Chun-Ping AU - Mao,Ze-Wei TI - Synthesis and anti-inflammatory evaluation of new chalcone derivatives bearing bispiperazine linker as IL-1β inhibitors SN - 1090-2120 PY - 2021///0224 KW - Animals KW - Anti-Inflammatory Agents, Non-Steroidal KW - chemical synthesis KW - Chalcone KW - Dose-Response Relationship, Drug KW - Interleukin-1beta KW - antagonists & inhibitors KW - Lipopolysaccharides KW - Mice KW - Mice, Inbred DBA KW - Molecular Structure KW - Nitric Oxide KW - Piperazine KW - chemistry KW - RAW 264.7 Cells KW - Structure-Activity Relationship N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.bioorg.2020.103748 ER -