Tang, Yan-Ling <br/><br/>
Synthesis and anti-inflammatory evaluation of new chalcone derivatives bearing bispiperazine linker as IL-1β inhibitors.  [electronic resource] 

 -  Bioorganic chemistry  05 2020 
 - 103748 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1090-2120 
<br/><br/><label>Standard No.: </label>10.1016/j.bioorg.2020.103748  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Anti-Inflammatory Agents, Non-Steroidal--chemical synthesis<br/>Chalcone--chemical synthesis<br/>Dose-Response Relationship, Drug<br/>Interleukin-1beta--antagonists & inhibitors<br/>Lipopolysaccharides--antagonists & inhibitors<br/>Mice<br/>Mice, Inbred DBA<br/>Molecular Structure<br/>Nitric Oxide--antagonists & inhibitors<br/>Piperazine--chemistry<br/>RAW 264.7 Cells<br/>Structure-Activity Relationship