TY - GEN AU - Fortin,Jerome AU - Tian,Ruxiao AU - Zarrabi,Ida AU - Hill,Graham AU - Williams,Eleanor AU - Sanchez-Duffhues,Gonzalo AU - Thorikay,Midory AU - Ramachandran,Parameswaran AU - Siddaway,Robert AU - Wong,Jong Fu AU - Wu,Annette AU - Apuzzo,Lorraine N AU - Haight,Jillian AU - You-Ten,Annick AU - Snow,Bryan E AU - Wakeham,Andrew AU - Goldhamer,David J AU - Schramek,Daniel AU - Bullock,Alex N AU - Dijke,Peter Ten AU - Hawkins,Cynthia AU - Mak,Tak W TI - Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas SN - 1878-3686 PY - 2020///0810 KW - Activin Receptors, Type I KW - antagonists & inhibitors KW - Animals KW - Basic Helix-Loop-Helix Transcription Factors KW - genetics KW - Bone Morphogenetic Proteins KW - Brain Neoplasms KW - drug therapy KW - Cell Differentiation KW - Cell Line, Tumor KW - Class I Phosphatidylinositol 3-Kinases KW - Female KW - Glioma KW - Histones KW - Humans KW - Lactones KW - pharmacology KW - Male KW - Mice, Transgenic KW - Mutation KW - Neoplasms, Experimental KW - Neuroglia KW - metabolism KW - Oligodendroglia KW - pathology KW - Receptor, Platelet-Derived Growth Factor alpha KW - SOXC Transcription Factors N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.ccell.2020.02.002 ER -