TY - GEN AU - Che,Tao AU - English,Justin AU - Krumm,Brian E AU - Kim,Kuglae AU - Pardon,Els AU - Olsen,Reid H J AU - Wang,Sheng AU - Zhang,Shicheng AU - Diberto,Jeffrey F AU - Sciaky,Noah AU - Carroll,F Ivy AU - Steyaert,Jan AU - Wacker,Daniel AU - Roth,Bryan L TI - Nanobody-enabled monitoring of kappa opioid receptor states SN - 2041-1723 PY - 2020///0522 KW - Allosteric Site KW - Binding Sites KW - Biosensing Techniques KW - Crystallography, X-Ray KW - Cyclic AMP KW - metabolism KW - Dynorphins KW - chemistry KW - HEK293 Cells KW - Humans KW - Luminescent Measurements KW - methods KW - Piperazines KW - Piperidines KW - Protein Conformation KW - Pyrrolidines KW - Receptors, G-Protein-Coupled KW - Receptors, Opioid, kappa KW - agonists KW - Recombinant Proteins KW - Single-Domain Antibodies KW - Tetrahydroisoquinolines N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1038/s41467-020-14889-7 ER -