TY - GEN AU - Liu,Ming AU - Yan,Qian AU - Sun,Yi AU - Nam,Yoonhee AU - Hu,Liang AU - Loong,Jane Hc AU - Ouyang,Qi AU - Zhang,Yu AU - Li,Hao-Long AU - Kong,Fan-En AU - Li,Lei AU - Li,Yan AU - Li,Mei-Mei AU - Cheng,Wei AU - Jiang,Ling-Xi AU - Fang,Shuo AU - Yang,Xiao-Dong AU - Mo,Jia-Qiang AU - Gong,Yuan-Feng AU - Tang,Yun-Qiang AU - Li,Yan AU - Yuan,Yun-Fei AU - Ma,Ning-Fang AU - Lin,Ge AU - Ma,Stephanie AU - Wang,Ji-Guang AU - Guan,Xin-Yuan TI - A hepatocyte differentiation model reveals two subtypes of liver cancer with different oncofetal properties and therapeutic targets SN - 1091-6490 PY - 2020///0713 KW - Aminopyridines KW - pharmacology KW - Animals KW - Biomarkers, Tumor KW - antagonists & inhibitors KW - Carcinoma, Hepatocellular KW - genetics KW - Cell Differentiation KW - drug effects KW - Cell Line KW - Cell Transformation, Neoplastic KW - Cohort Studies KW - Disease-Free Survival KW - E2F1 Transcription Factor KW - Female KW - Gene Expression Profiling KW - Gene Expression Regulation, Developmental KW - Gene Expression Regulation, Neoplastic KW - Hepatectomy KW - Hepatocytes KW - pathology KW - Human Embryonic Stem Cells KW - Humans KW - Hydroxyquinolines KW - Isoquinolines KW - Kaplan-Meier Estimate KW - Liver KW - growth & development KW - Liver Neoplasms KW - Male KW - Mice KW - Middle Aged KW - Prognosis KW - Pyridines KW - Pyrroles KW - Signal Transduction KW - Smad3 Protein KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1073/pnas.1912146117 ER -