Liu, Ming

A hepatocyte differentiation model reveals two subtypes of liver cancer with different oncofetal properties and therapeutic targets. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America 03 2020 - 6103-6113 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1091-6490

10.1073/pnas.1912146117 doi


Aminopyridines--pharmacology
Animals
Biomarkers, Tumor--antagonists & inhibitors
Carcinoma, Hepatocellular--genetics
Cell Differentiation--drug effects
Cell Line
Cell Transformation, Neoplastic--drug effects
Cohort Studies
Disease-Free Survival
E2F1 Transcription Factor--antagonists & inhibitors
Female
Gene Expression Profiling
Gene Expression Regulation, Developmental
Gene Expression Regulation, Neoplastic
Hepatectomy
Hepatocytes--pathology
Human Embryonic Stem Cells
Humans
Hydroxyquinolines--pharmacology
Isoquinolines--pharmacology
Kaplan-Meier Estimate
Liver--growth & development
Liver Neoplasms--genetics
Male
Mice
Middle Aged
Prognosis
Pyridines--pharmacology
Pyrroles--pharmacology
Signal Transduction--genetics
Smad3 Protein--antagonists & inhibitors
Xenograft Model Antitumor Assays