TY - GEN AU - Zhao,Ang AU - Zhang,Zhanjie AU - Zhou,Yanfen AU - Li,Xin AU - Li,Xiaotian AU - Ma,Bo AU - Zhang,Qi TI - β-Elemonic acid inhibits the growth of human Osteosarcoma through endoplasmic reticulum (ER) stress-mediated PERK/eIF2α/ATF4/CHOP activation and Wnt/β-catenin signal suppression SN - 1618-095X PY - 2020///0803 KW - Activating Transcription Factor 4 KW - metabolism KW - Animals KW - Antineoplastic Agents, Phytogenic KW - pharmacokinetics KW - Apoptosis KW - drug effects KW - Bone Neoplasms KW - drug therapy KW - Cell Line, Tumor KW - Cell Movement KW - Cell Proliferation KW - Endoplasmic Reticulum Stress KW - Eukaryotic Initiation Factor-2 KW - G1 Phase Cell Cycle Checkpoints KW - Humans KW - Male KW - Mice, Inbred BALB C KW - Osteosarcoma KW - Phenanthrenes KW - pharmacology KW - Tissue Distribution KW - Transcription Factor CHOP KW - genetics KW - Triterpenes KW - Wnt Signaling Pathway KW - Xenograft Model Antitumor Assays KW - beta Catenin KW - eIF-2 Kinase N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.phymed.2020.153183 ER -