TY  - GEN
AU  - Liddle,John
AU  - Hutchinson,Jonathan P
AU  - Kitchen,Semra
AU  - Rowland,Paul
AU  - Neu,Margarete
AU  - Cecconie,Ted
AU  - Holmes,Duncan S
AU  - Jones,Emma
AU  - Korczynska,Justyna
AU  - Koumantou,Despoina
AU  - Lea,Jonathan D
AU  - Nickels,Leng
AU  - Pemberton,Michelle
AU  - Phillipou,Alex
AU  - Schneck,Jessica L
AU  - Sheehan,Hester
AU  - Tinworth,Christopher P
AU  - Uings,Iain
AU  - Wojno-Picon,Justyna
AU  - Young,Robert J
AU  - Stratikos,Efstratios
TI  - Targeting the Regulatory Site of ER Aminopeptidase 1 Leads to the Discovery of a Natural Product Modulator of Antigen Presentation
SN  - 1520-4804
PY  - 2020///0914
KW  - Allosteric Site
KW  - Aminopeptidases
KW  - antagonists & inhibitors
KW  - Animals
KW  - Antigen Presentation
KW  - drug effects
KW  - Catalytic Domain
KW  - Crystallography, X-Ray
KW  - Diterpenes, Clerodane
KW  - chemistry
KW  - Enzyme Activators
KW  - Epitopes
KW  - HeLa Cells
KW  - Humans
KW  - Mice
KW  - Minor Histocompatibility Antigens
KW  - Peptides
KW  - Protease Inhibitors
KW  - Protein Binding
KW  - Proteolysis
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/acs.jmedchem.9b02123
ER  -