Chaves, Sílvia <br/><br/>
Design, Synthesis, and In Vitro Evaluation of Hydroxybenzimidazole-Donepezil Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease.  [electronic resource] 

 -  Molecules (Basel, Switzerland)  Feb 2020 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1420-3049 
<br/><br/><label>Standard No.: </label>10.3390/molecules25040985  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetylcholinesterase--chemistry<br/>Alzheimer Disease--drug therapy<br/>Amyloid beta-Peptides--antagonists & inhibitors<br/>Antioxidants--chemical synthesis<br/>Chelating Agents--chemical synthesis<br/>Cholinesterase Inhibitors--chemical synthesis<br/>Donepezil--analogs & derivatives<br/>Humans<br/>Indazoles--chemistry<br/>Ligands<br/>Molecular Docking Simulation<br/>Molecular Structure<br/>Piperazine--chemical synthesis<br/>Piperidines--chemical synthesis<br/>Structure-Activity Relationship