TY - GEN AU - Wang,Yudong AU - Janku,Filip AU - Piha-Paul,Sarina AU - Hess,Kenneth AU - Broaddus,Russell AU - Liu,Lidong AU - Shi,Naiyi AU - Overman,Michael AU - Kopetz,Scott AU - Subbiah,Vivek AU - Naing,Aung AU - Hong,David AU - Tsimberidou,Apostolia M AU - Karp,Daniel AU - Yao,James AU - Fu,Siqing TI - Phase I studies of vorinostat with ixazomib or pazopanib imply a role of antiangiogenesis-based therapy for TP53 mutant malignancies SN - 2045-2322 PY - 2020///1112 KW - Adult KW - Aged KW - Angiogenesis Inhibitors KW - adverse effects KW - Boron Compounds KW - Glycine KW - Humans KW - Indazoles KW - Kaplan-Meier Estimate KW - Middle Aged KW - Mutation KW - genetics KW - Neoplasms KW - drug therapy KW - Progression-Free Survival KW - Pyrimidines KW - Sulfonamides KW - Treatment Outcome KW - Tumor Suppressor Protein p53 KW - Vorinostat KW - Young Adult N1 - Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41598-020-58366-z ER -