TY  - GEN
AU  - Mitra,Mayur S
AU  - Lancaster,Karla
AU  - Adedeji,Adeyemi O
AU  - Palanisamy,Gopinath S
AU  - Dave,Rutwij A
AU  - Zhong,Fiona
AU  - Holdren,Matthew S
AU  - Turley,Shannon J
AU  - Liang,Wei-Ching
AU  - Wu,Yan
AU  - Meng,Y Gloria
AU  - Vernes,Jean-Michel
AU  - Schutten,Melissa M
TI  - A Potent Pan-TGFβ Neutralizing Monoclonal Antibody Elicits Cardiovascular Toxicity in Mice and Cynomolgus Monkeys
SN  - 1096-0929
PY  - 2021///0601
KW  - Animals
KW  - Antibodies, Monoclonal, Humanized
KW  - blood
KW  - Antibodies, Neutralizing
KW  - Cardiotoxicity
KW  - Cardiovascular Diseases
KW  - chemically induced
KW  - Cell Line
KW  - Female
KW  - Heart
KW  - drug effects
KW  - Hemorrhage
KW  - Humans
KW  - Macaca fascicularis
KW  - Male
KW  - Mice
KW  - Myocardium
KW  - metabolism
KW  - Risk Assessment
KW  - Time Factors
KW  - Toxicity Tests
KW  - Toxicokinetics
KW  - Transforming Growth Factor beta
KW  - antagonists & inhibitors
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1093/toxsci/kfaa024
ER  -