TY  - GEN
AU  - Wei,Yao
AU  - Lu,Ming
AU  - Mei,Meng
AU  - Wang,Haoran
AU  - Han,Zhitao
AU  - Chen,Miaomiao
AU  - Yao,Hang
AU  - Song,Nanshan
AU  - Ding,Xiao
AU  - Ding,Jianhua
AU  - Xiao,Ming
AU  - Hu,Gang
TI  - Pyridoxine induces glutathione synthesis via PKM2-mediated Nrf2 transactivation and confers neuroprotection
SN  - 2041-1723
PY  - 2020///0505
KW  - Animals
KW  - Astrocytes
KW  - Behavior Observation Techniques
KW  - Behavior, Animal
KW  - drug effects
KW  - Cells, Cultured
KW  - Dopamine
KW  - metabolism
KW  - Dopaminergic Neurons
KW  - Glutathione
KW  - biosynthesis
KW  - MPTP Poisoning
KW  - diagnosis
KW  - Mice, Knockout
KW  - NF-E2-Related Factor 2
KW  - genetics
KW  - Neuroprotective Agents
KW  - administration & dosage
KW  - Oxidative Stress
KW  - Primary Cell Culture
KW  - Protein Multimerization
KW  - Pyridoxine
KW  - Pyruvate Kinase
KW  - Reactive Oxygen Species
KW  - Receptors, Dopamine D2
KW  - Substantia Nigra
KW  - cytology
KW  - Transcriptional Activation
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/s41467-020-14788-x
ER  -