TY - GEN AU - Dargue,Rebecca AU - Zia,Rabiya AU - Lau,Chungho AU - Nicholls,Andrew W AU - Dare,Theo O AU - Lee,Karla AU - Jalan,Rajiv AU - Coen,Muireann AU - Wilson,Ian D TI - Metabolism and Effects on Endogenous Metabolism of Paracetamol (Acetaminophen) in a Porcine Model of Liver Failure SN - 1096-0929 PY - 2021///0601 KW - Acetaminophen KW - metabolism KW - Animals KW - Biotransformation KW - Chemical and Drug Induced Liver Injury KW - etiology KW - Chromatography, Liquid KW - Disease Models, Animal KW - Female KW - Kidney KW - drug effects KW - Liver KW - Liver Failure KW - chemically induced KW - Metabolome KW - Metabolomics KW - Mitochondria, Liver KW - Proton Magnetic Resonance Spectroscopy KW - Sus scrofa KW - Tandem Mass Spectrometry KW - Tissue Distribution N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1093/toxsci/kfaa023 ER -