TY - GEN AU - Hurkmans,Daan P AU - Kuipers,Merian E AU - Smit,Jasper AU - van Marion,Ronald AU - Mathijssen,Ron H J AU - Postmus,Piet E AU - Hiemstra,Pieter S AU - Aerts,Joachim G J V AU - von der Thüsen,Jan H AU - van der Burg,Sjoerd H TI - Tumor mutational load, CD8 SN - 1432-0851 PY - 2020///0508 KW - Aged KW - Antineoplastic Agents, Immunological KW - pharmacology KW - B7-H1 Antigen KW - analysis KW - Biomarkers, Tumor KW - Biopsy KW - CD8-Positive T-Lymphocytes KW - immunology KW - Carcinoma, Non-Small-Cell Lung KW - drug therapy KW - Clinical Decision-Making KW - methods KW - Disease Progression KW - Female KW - Follow-Up Studies KW - Histocompatibility Antigens Class I KW - Humans KW - Lung KW - pathology KW - Lung Neoplasms KW - Lymphocytes, Tumor-Infiltrating KW - Male KW - Middle Aged KW - Mutation Rate KW - Nivolumab KW - Predictive Value of Tests KW - Progression-Free Survival KW - Proof of Concept Study KW - Prospective Studies KW - Response Evaluation Criteria in Solid Tumors KW - Retrospective Studies N1 - Publication Type: Journal Article UR - https://doi.org/10.1007/s00262-020-02506-x ER -