TY - GEN AU - Yao,Shihua AU - Nguyen,Tuong-Vi AU - Rolfe,Alan AU - Agrawal,Anant A AU - Ke,Jiyuan AU - Peng,Shouyong AU - Colombo,Federico AU - Yu,Sean AU - Bouchard,Patricia AU - Wu,Jiayi AU - Huang,Kuan-Chun AU - Bao,Xingfeng AU - Omoto,Kiyoyuki AU - Selvaraj,Anand AU - Yu,Lihua AU - Ioannidis,Stephanos AU - Vaillancourt,Frédéric H AU - Zhu,Ping AU - Larsen,Nicholas A AU - Bolduc,David M TI - Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket SN - 2451-9448 PY - 2021///0701 KW - Adenosine Triphosphate KW - antagonists & inhibitors KW - Allosteric Regulation KW - drug effects KW - Carbamoyl-Phosphate Synthase (Ammonia) KW - Dose-Response Relationship, Drug KW - Enzyme Inhibitors KW - chemistry KW - Humans KW - Hydrolysis KW - Models, Molecular KW - Molecular Structure KW - Piperidines KW - Small Molecule Libraries KW - Thiazoles N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.chembiol.2020.01.009 ER -