Yao, Shihua
Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket. [electronic resource]
- Cell chemical biology 03 2020
- 259-268.e5 p. digital
Publication Type: Journal Article
2451-9448
10.1016/j.chembiol.2020.01.009 doi
Adenosine Triphosphate--antagonists & inhibitors
Allosteric Regulation--drug effects
Carbamoyl-Phosphate Synthase (Ammonia)--antagonists & inhibitors
Dose-Response Relationship, Drug
Enzyme Inhibitors--chemistry
Humans
Hydrolysis--drug effects
Models, Molecular
Molecular Structure
Piperidines--chemistry
Small Molecule Libraries--chemistry
Thiazoles--chemistry