TY - GEN AU - Chan,Brandon Y H AU - Roczkowsky,Andrej AU - Cho,Woo Jung AU - Poirier,Mathieu AU - Sergi,Consolato AU - Keschrumrus,Vic AU - Churko,Jared M AU - Granzier,Henk AU - Schulz,Richard TI - MMP inhibitors attenuate doxorubicin cardiotoxicity by preventing intracellular and extracellular matrix remodelling SN - 1755-3245 PY - 2021///1006 KW - Animals KW - Cardiotoxicity KW - Cell Line KW - Disease Models, Animal KW - Doxorubicin KW - Doxycycline KW - pharmacology KW - Extracellular Matrix KW - drug effects KW - Fibrosis KW - Heart Diseases KW - chemically induced KW - Human Embryonic Stem Cells KW - Humans KW - Male KW - Matrix Metalloproteinase 2 KW - metabolism KW - Matrix Metalloproteinase Inhibitors KW - Mice, Inbred C57BL KW - Mitochondria, Heart KW - Myocytes, Cardiac KW - Phenyl Ethers KW - Protein Kinases KW - Proteolysis KW - Ventricular Function, Left KW - Ventricular Remodeling KW - Mice N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1093/cvr/cvaa017 ER -