Tenkumo, Taichi <br/><br/>
Reduction of inflammation in a chronic periodontitis model in rats by TNF-α gene silencing with a topically applied siRNA-loaded calcium phosphate paste.  [electronic resource] 

 -  Acta biomaterialia  03 2020 
 - 263-279 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1878-7568 
<br/><br/><label>Standard No.: </label>10.1016/j.actbio.2020.01.031  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alkaline Phosphatase--metabolism<br/>Animals<br/>Anti-Inflammatory Agents--pharmacology<br/>Calcium Phosphates--chemistry<br/>Cell Line<br/>Cell Survival--drug effects<br/>Chronic Periodontitis--diagnostic imaging<br/>Disease Models, Animal<br/>Gene Silencing<br/>Gingiva--pathology<br/>Inflammation--pathology<br/>Male<br/>Mice, Inbred C57BL<br/>Monocytes--cytology<br/>Nanoparticles--chemistry<br/>Particle Size<br/>RNA, Small Interfering--metabolism<br/>Rats, Wistar<br/>Tartrate-Resistant Acid Phosphatase--metabolism<br/>Tumor Necrosis Factor-alpha--genetics<br/>Wound Healing--drug effects<br/>X-Ray Microtomography