Anticancer activity of dietary xanthone α-mangostin against hepatocellular carcinoma by inhibition of STAT3 signaling via stabilization of SHP1. [electronic resource]
- Cell death & disease 01 2020
- 63 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2041-4889
10.1038/s41419-020-2227-4 doi
Animals Antineoplastic Agents--chemistry Apoptosis--drug effects Carcinoma, Hepatocellular--genetics Cell Cycle Checkpoints--drug effects Cell Line, Tumor Cell Nucleus--drug effects Cell Proliferation--drug effects Diet Gene Expression Regulation, Neoplastic--drug effects Humans Liver Neoplasms--genetics Mice, Nude Phosphorylation--drug effects Protein Multimerization--drug effects Protein Transport--drug effects Protein Tyrosine Phosphatase, Non-Receptor Type 6--metabolism STAT3 Transcription Factor--metabolism Signal Transduction--drug effects Xanthones--chemistry Xenograft Model Antitumor Assays