TY - GEN AU - Cristea,Sandra AU - Coles,Garry L AU - Hornburg,Daniel AU - Gershkovitz,Maya AU - Arand,Julia AU - Cao,Siqi AU - Sen,Triparna AU - Williamson,Stuart C AU - Kim,Jun W AU - Drainas,Alexandros P AU - He,Andrew AU - Cam,Laurent Le AU - Byers,Lauren Averett AU - Snyder,Michael P AU - Contrepois,Kévin AU - Sage,Julien TI - The MEK5-ERK5 Kinase Axis Controls Lipid Metabolism in Small-Cell Lung Cancer SN - 1538-7445 PY - 2020///1014 KW - Animals KW - Atorvastatin KW - pharmacology KW - Cell Line, Tumor KW - Cell Survival KW - drug effects KW - Cholesterol KW - biosynthesis KW - Gene Knockdown Techniques KW - Humans KW - Hydroxymethylglutaryl CoA Reductases KW - metabolism KW - Hydroxymethylglutaryl-CoA Reductase Inhibitors KW - Lipid Metabolism KW - Lipidomics KW - Lung Neoplasms KW - drug therapy KW - MAP Kinase Kinase 5 KW - genetics KW - MAP Kinase Signaling System KW - Mevalonic Acid KW - Mice KW - Mitogen-Activated Protein Kinase 7 KW - RNA-Seq KW - Small Cell Lung Carcinoma KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1158/0008-5472.CAN-19-1027 ER -