TY - GEN AU - Romero,Celeste AU - Lambert,Lester J AU - Sheffler,Douglas J AU - De Backer,Laurent J S AU - Raveendra-Panickar,Dhanya AU - Celeridad,Maria AU - Grotegut,Stefan AU - Rodiles,Socorro AU - Holleran,John AU - Sergienko,Eduard AU - Pasquale,Elena B AU - Cosford,Nicholas D P AU - Tautz,Lutz TI - A cellular target engagement assay for the characterization of SHP2 (PTPN11) phosphatase inhibitors SN - 1083-351X PY - 2020///1021 KW - Animals KW - Carcinogenesis KW - genetics KW - Cell Line KW - Drug Discovery KW - methods KW - Enzyme Inhibitors KW - metabolism KW - Gain of Function Mutation KW - Humans KW - Protein Binding KW - Protein Tyrosine Phosphatase, Non-Receptor Type 11 KW - antagonists & inhibitors KW - Proto-Oncogene Mas N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1074/jbc.RA119.010838 ER -